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Massive antibody discovery used to probe structure–function relationships of the essential outer membrane protein LptD
Outer membrane proteins (OMPs) in Gram-negative bacteria dictate permeability of metabolites, antibiotics, and toxins. Elucidating the structure-function relationships governing OMPs within native membrane environments remains challenging. We constructed a diverse library of >3000 monoclonal anti...
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| Pubblicato in: | eLife |
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| Autori principali: | , , , , , , , , , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
eLife Sciences Publications, Ltd
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6592684/ https://ncbi.nlm.nih.gov/pubmed/31237236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.46258 |
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