Restricted epitope specificity determined by variable region germline segment pairing in rodent antibody repertoires

Antibodies from B-cell clonal lineages share sequence and structural properties as well as epitope specificity. Clonally unrelated antibodies can similarly share sequence and specificity properties and are said to be convergent. Convergent antibody responses against several antigens have been descri...

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Publié dans:MAbs
Auteurs principaux: Hsiao, Yi-Chun, Chen, Ying-Jiun J., Goldstein, Leonard D., Wu, Jia, Lin, Zhonghua, Schneider, Kellen, Chaudhuri, Subhra, Antony, Aju, Bajaj Pahuja, Kanika, Modrusan, Zora, Seshasayee, Dhaya, Seshagiri, Somasekar, Hötzel, Isidro
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039645/
https://ncbi.nlm.nih.gov/pubmed/32041466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2020.1722541
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