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Cysteamine Protects Neurons from Mutant Huntingtin Toxicity

BACKGROUND: The potential benefit of cysteamine for Huntington’s disease has been demonstrated in HD animal models. Cysteamine and its derivate cystamine were shown to reduce neuropathology and prolong lifespan. Human studies have demonstrated safety, and suggestive results regarding efficacy. Despi...

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Detalhes bibliográficos
Publicado no:J Huntingtons Dis
Main Authors: Arbez, Nicolas, Roby, Elaine, Akimov, Sergey, Eddings, Chelsy, Ren, Mark, Wang, Xiaofang, Ross, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039181/
https://ncbi.nlm.nih.gov/pubmed/30856117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JHD-180312
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