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Cysteamine Protects Neurons from Mutant Huntingtin Toxicity

BACKGROUND: The potential benefit of cysteamine for Huntington’s disease has been demonstrated in HD animal models. Cysteamine and its derivate cystamine were shown to reduce neuropathology and prolong lifespan. Human studies have demonstrated safety, and suggestive results regarding efficacy. Despi...

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Bibliografski detalji
Izdano u:J Huntingtons Dis
Glavni autori: Arbez, Nicolas, Roby, Elaine, Akimov, Sergey, Eddings, Chelsy, Ren, Mark, Wang, Xiaofang, Ross, Christopher A.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039181/
https://ncbi.nlm.nih.gov/pubmed/30856117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JHD-180312
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