Discovery of small molecule inhibitors of Leishmania braziliensis Hsp90 chaperone

Leishmaniasis is a neglected disease caused by the protozoa Leishmania ssp. Environmental differences found by the parasites in the vector and the host are translated into cellular stress, leading to the production of heat shock proteins (Hsp). These are molecular chaperones involved in the folding...

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Pubblicato in:J Enzyme Inhib Med Chem
Autori principali: Batista, Fernanda A. H., Ramos, Sérgio L., Tassone, Giusy, Leitão, Andrei, Montanari, Carlos A., Botta, Maurizio, Mori, Mattia, Borges, Júlio C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2020
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7034072/
https://ncbi.nlm.nih.gov/pubmed/32048531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2020.1726342
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