Discovery of small molecule inhibitors of Leishmania braziliensis Hsp90 chaperone

Leishmaniasis is a neglected disease caused by the protozoa Leishmania ssp. Environmental differences found by the parasites in the vector and the host are translated into cellular stress, leading to the production of heat shock proteins (Hsp). These are molecular chaperones involved in the folding...

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Bibliografiska uppgifter
I publikationen:J Enzyme Inhib Med Chem
Huvudupphovsmän: Batista, Fernanda A. H., Ramos, Sérgio L., Tassone, Giusy, Leitão, Andrei, Montanari, Carlos A., Botta, Maurizio, Mori, Mattia, Borges, Júlio C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2020
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7034072/
https://ncbi.nlm.nih.gov/pubmed/32048531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2020.1726342
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