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COMPARTMENTALIZED CANCER DRUG DISCOVERY TARGETING MITOCHONDRIAL Hsp90 CHAPERONES

There is a plethora of attractive drug targets in cancer, but their therapeutic exploitation proved more difficult than expected, and only rarely truly successful. One possibility not often considered in drug discovery is that cancer signaling pathways are not randomly arranged in cells, but orchest...

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Detalhes bibliográficos
Main Authors: Kang, Byoung Heon, Altieri, Dario C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766018/
https://ncbi.nlm.nih.gov/pubmed/19648961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.227
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