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PRECLINICAL CHARACTERIZATION OF MITOCHONDRIA-TARGETED SMALL MOLECULE Hsp90 INHIBITORS, GAMITRINIBS, IN ADVANCED PROSTATE CANCER
PURPOSE: To characterize the preclinical activity of the first class of combinatorial, mitochondria-targeted, small molecule Hsp90 inhibitors, Gamitrinibs, in models of hormone-refractory, drug-resistant and localized and bone metastatic prostate cancer, in vivo. EXPERIMENTAL DESIGN: Mitochondrial p...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2948625/ https://ncbi.nlm.nih.gov/pubmed/20876793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-1818 |
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