Development of a PC12 Cell Based Assay for Screening Catechol-O-methyltransferase Inhibitors

[Image: see text] The male rat adrenal pheochromocytoma cell-derived PC12 cell line can synthesize and release catecholamine neurotransmitters, and it has been widely used as a model system in cell biology and toxicology research. Catechol-O-methyltransferase (COMT) is involved in the inactivation o...

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Xehetasun bibliografikoak
Argitaratua izan da:ACS Chem Neurosci
Egile Nagusiak: Zhang, Gongliang, Buchler, Ingrid P., DePasquale, Michael, Wormald, Michael, Liao, Gangling, Wei, Huijun, Barrow, James C., Carr, Gregory V.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Chemical Society 2019
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032882/
https://ncbi.nlm.nih.gov/pubmed/31491076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.9b00395
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