Development of a PC12 Cell Based Assay for Screening Catechol-O-methyltransferase Inhibitors

di Zhang, Gongliang, Buchler, Ingrid P., DePasquale, Michael, Wormald, Michael, Liao, Gangling, Wei, Huijun, Barrow, James C., Carr, Gregory V.
Pubblicato in ACS Chem Neurosci (2019)

Novel, non-nitrocatechol catechol-O-methyltransferase inhibitors modulate dopamine neurotransmission in the frontal cortex and improve cognitive flexibility

di Byers, Spencer, Buchler, Ingrid P., DePasquale, Michael, Rowley, Helen L., Kulkarni, Rajiv S., Pinder, Lucy, Kolobova, Anna, Li, Cailian, Au, Vinh, Akuma, Daniel, Zhang, Gongliang, Wei, Huijun, Cheetham, Sharon C., Barrow, James C., Carr, Gregory V.
Pubblicato in Psychopharmacology (Berl) (2020)

Synthesis and Evaluation of Bicyclic Hydroxypyridones as Inhibitors of Catechol O-Methyltransferase

di Ernst, Glen, Akuma, Daniel, Au, Vinh, Buchler, Ingrid P., Byers, Spencer, Carr, Gregory V., Defays, Sabine, de León, Pablo, Demaude, Thierry, DePasquale, Michael, Durieu, Véronique, Huang, Yifang, Jigorel, Emilie, Kimos, Martha, Kolobova, Anna, Montel, Florian, Moureau, Florence, Poslusney, Michael, Swinnen, Dominique, Vandergeten, Marie-Christine, Van houtvin, Nathalie, Wei, Huijun, White, Noelle, Wood, Martyn, Barrow, James C.
Pubblicato in ACS Med Chem Lett (2019)

Aminopyrazole Carboxamide Bruton’s Tyrosine Kinase Inhibitors. Irreversible to Reversible Covalent Reactive Group Tuning

di Schnute, Mark E., Benoit, Stephen E., Buchler, Ingrid P., Caspers, Nicole, Grapperhaus, Margaret L., Han, Seungil, Hotchandani, Rajeev, Huang, Nelson, Hughes, Robert O., Juba, Brian M., Kim, Kyung-Hee, Liu, Erica, McCarthy, Erin, Messing, Dean, Miyashiro, Joy S., Mohan, Shashi, O’Connell, Thomas N., Ohren, Jeffrey F., Parikh, Mihir D., Schmidt, Michelle, Selness, Shaun R., Springer, John R., Thanabal, Venkataraman, Trujillo, John I., Walker, Daniel P., Wan, Zhao-Kui, Withka, Jane M., Wittwer, Arthur J., Wood, Nancy L., Xing, Li, Zapf, Christoph W., Douhan, John
Pubblicato in ACS Med Chem Lett (2018)