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The structure of the infectious prion protein: Experimental data and molecular models

The structures of the infectious prion protein, PrP(Sc), and that of its proteolytically truncated variant, PrP 27–30, have evaded experimental determination due to their insolubility and propensity to aggregate. Molecular modeling has been used to fill this void and to predict their structures, but...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Prion
Hauptverfasser: Requena, Jesús R, Wille, Holger
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7030906/
https://ncbi.nlm.nih.gov/pubmed/24583975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.28368
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