A carregar...
Preclinical studies reveal MLN4924 is a promising new retinoblastoma therapy
RB1 loss (RB1(null)) or MYCN amplification (MYCN(amp)) in fetal human retina causes retinoblastoma. SKP2 loss kills RB1(null) cells, but small molecule SKP2 inhibitors remain unexplored therapeutically. Whether SKP2 is synthetic lethal in MYCN(amp) retinoblastoma is unclear. SKP2 is the substrate re...
Na minha lista:
| Publicado no: | Cell Death Discov |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7026052/ https://ncbi.nlm.nih.gov/pubmed/32123578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-020-0237-8 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|