Functional genomics identifies new synergistic therapies for retinoblastoma

Local intravitreal or intra-arterial chemotherapy has improved therapeutic success for the pediatric cancer retinoblastoma (RB), but toxicity remains a major caveat. RB initiates primarily with RB1 loss or, rarely, MYCN amplification, but the critical downstream networks are incompletely understood....

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Dettagli Bibliografici
Pubblicato in:Oncogene
Autori principali: Aubry, Arthur, Pearson, Joel D., Huang, Katherine, Livne-bar, Izhar, Ahmad, Mohammad, Jagadeesan, Madhavan, Khetan, Vikas, Ketela, Troy, Brown, Kevin R., Yu, Tao, Lu, Suying, Wrana, Jeffrey L., Moffat, Jason, Bremner, Rod
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7391301/
https://ncbi.nlm.nih.gov/pubmed/32572160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-1372-7
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