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Synthetic bPNAs as allosteric triggers of hammerhead ribozyme catalysis
The biochemistry and structural biology of the hammerhead ribozyme (HHR) have been well elucidated. The secondary and tertiary structural elements that enable sugar–phosphate bond scission to be catalyzed by this RNA are clearly understood. We have taken advantage of this knowledge base to test the...
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| Udgivet i: | Methods Enzymol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7023910/ https://ncbi.nlm.nih.gov/pubmed/31239045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2019.04.028 |
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