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Synthetic bPNAs as allosteric triggers of hammerhead ribozyme catalysis
The biochemistry and structural biology of the hammerhead ribozyme (HHR) have been well elucidated. The secondary and tertiary structural elements that enable sugar–phosphate bond scission to be catalyzed by this RNA are clearly understood. We have taken advantage of this knowledge base to test the...
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| 發表在: | Methods Enzymol |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7023910/ https://ncbi.nlm.nih.gov/pubmed/31239045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2019.04.028 |
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