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A Randomized, Placebo-Controlled, Double-Blind, Dose Escalation, Single Dose and Steady State Pharmacokinetics Study of 9cUAB30 in Healthy Volunteers

9cUAB30 is a synthetic analog of 9-cis retinoic acid with chemoprevention activity in cell lines and animal models. The purpose of this phase I placebo-controlled, double-blinded, dose escalation study of 9cUAB30 was to evaluate its safety, pharmacokinetics, and determine a dose for future phase II...

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Bibliografiske detaljer
Udgivet i:Cancer Prev Res (Phila)
Main Authors: Kolesar, Jill M., Andrews, Shannon, Green, Heather, Havighurst, Tom C., Wollmer, Barbara W., DeShong, Katina, Laux, Douglas E, Krontiras, Helen, Muccio, Donald D., Kim, KyungMann, Grubbs, Clinton J., House, Margaret G., Parnes, Howard L., Heckman-Stoddard, Brandy M., Bailey, Howard H.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7008944/
https://ncbi.nlm.nih.gov/pubmed/31484659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-19-0310
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