A Pilot, First-in-Human, Pharmacokinetic Study of 9cUAB30 in Healthy Volunteers

9cUAB30 is a synthetic analog of 9-cis-retinoic acid with chemopreventive activity in cell lines and in animal models. The purpose of this first-in-human evaluation of 9cUAB30 was to evaluate the single-dose pharmacokinetic profile and toxicity of the compound in healthy volunteers at 3 dose levels....

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Hlavní autoři: Kolesar, Jill M., Hoel, Ryan, Pomplun, Marcia, Havighurst, Tom, Stublaski, Jeanne, Wollmer, Barbara, Krontiras, Helen, Brouillette, Wayne, Muccio, Donald, Kim, KyungMann, Grubbs, Clinton J., Bailey, Howard E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204611/
https://ncbi.nlm.nih.gov/pubmed/21149332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-10-0149
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