Prevention of KLF4-mediated tumor initiation and malignant transformation by UAB30 rexinoid

The transcription factor KLF4 acts in post-mitotic epithelial cells to promote differentiation, and functions in a context-dependent fashion as an oncogene. In the skin KLF4 is co-expressed with the nuclear receptors RARγ and RXRα, and formation of the skin permeability barrier is a shared function...

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Main Authors: Jiang, Wen, Deng, Wentao, Bailey, Sarah K., Nail, Clint D., Frost, Andra R., Brouillette, Wayne J., Muccio, Donald D., Grubbs, Clinton J., Ruppert, J. Michael, Lobo-Ruppert, Susan M.
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776760/
https://ncbi.nlm.nih.gov/pubmed/19197145
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