Conformationally Defined Rexinoids and Their Efficacy in the Prevention of Mammary Cancers

(2E,4E,6Z,8Z)-8-(3′,4′-Dihydro-1′(2H)-naphthalen-1′-ylidene)-3,7-dimethyl-2,3,6-octatrienoinic acid (UAB30) is currently undergoing clinical evaluation as a novel cancer prevention agent. In efforts to develop even more highly potent rexinoids that prevent breast cancer without toxicity, we further...

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Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Atigadda, Venkatram R., Xia, Gang, Deshpande, Anil, Wu, Lizhi, Kedishvili, Natalia, Smith, Craig D., Krontiras, Helen, Bland, Kirby I., Grubbs, Clinton J., Brouillette, Wayne J., Muccio, Donald D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4928877/
https://ncbi.nlm.nih.gov/pubmed/26331194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.5b00829
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