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A phase II randomized, double-blind, presurgical trial of Polyphenon E in bladder cancer patients to evaluate pharmacodynamics and bladder tissue biomarkers

We performed a phase 2 pharmacodynamic, prevention trial of Polyphenon E(®) (a green tea polyphenol formulation primarily consisting of epigallocatechin gallate (EGCG)) in patients prior to bladder cancer surgery. Patients with a bladder tumor were randomized to receive Polyphenon E(®) containing ei...

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Détails bibliographiques
Publié dans:Cancer Prev Res (Phila)
Auteurs principaux: Gee, Jason R., Saltzstein, Daniel R., Kim, KyungMann, Kolesar, Jill, Huang, Wei, Havighurst, Thomas C., Wollmer, Barbara W, Stublaski, Jeanne, Downs, Tracy, Mukhtar, Hasan, House, Margaret G., Parnes, Howard L., Bailey, Howard H.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503683/
https://ncbi.nlm.nih.gov/pubmed/28325826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-16-0167
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