A phase II randomized, double-blind, presurgical trial of Polyphenon E in bladder cancer patients to evaluate pharmacodynamics and bladder tissue biomarkers

We performed a phase 2 pharmacodynamic, prevention trial of Polyphenon E(®) (a green tea polyphenol formulation primarily consisting of epigallocatechin gallate (EGCG)) in patients prior to bladder cancer surgery. Patients with a bladder tumor were randomized to receive Polyphenon E(®) containing ei...

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Vydáno v:Cancer Prev Res (Phila)
Hlavní autoři: Gee, Jason R., Saltzstein, Daniel R., Kim, KyungMann, Kolesar, Jill, Huang, Wei, Havighurst, Thomas C., Wollmer, Barbara W, Stublaski, Jeanne, Downs, Tracy, Mukhtar, Hasan, House, Margaret G., Parnes, Howard L., Bailey, Howard H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503683/
https://ncbi.nlm.nih.gov/pubmed/28325826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-16-0167
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