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A phase II randomized, double-blind, presurgical trial of Polyphenon E in bladder cancer patients to evaluate pharmacodynamics and bladder tissue biomarkers

We performed a phase 2 pharmacodynamic, prevention trial of Polyphenon E(®) (a green tea polyphenol formulation primarily consisting of epigallocatechin gallate (EGCG)) in patients prior to bladder cancer surgery. Patients with a bladder tumor were randomized to receive Polyphenon E(®) containing ei...

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Detalhes bibliográficos
Publicado no:Cancer Prev Res (Phila)
Main Authors: Gee, Jason R., Saltzstein, Daniel R., Kim, KyungMann, Kolesar, Jill, Huang, Wei, Havighurst, Thomas C., Wollmer, Barbara W, Stublaski, Jeanne, Downs, Tracy, Mukhtar, Hasan, House, Margaret G., Parnes, Howard L., Bailey, Howard H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503683/
https://ncbi.nlm.nih.gov/pubmed/28325826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-16-0167
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