A Phase 2 Cancer Chemoprevention Biomarker Trial of Isoflavone G-2535 (Genistein) in Presurgical Bladder Cancer Patients

The soy compound genistein has been observed preclinically to inhibit bladder cancer growth with one potential mechanism being inhibition of epidermal growth factor receptor phosphorylation (p-EGFR). A phase 2 randomized, placebo-controlled trial investigated whether daily, oral genistein (300 or 60...

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Huvudupphovsmän: Messing, Edward, Gee, Jason R., Saltzstein, Daniel R., Kim, KyungMann, diSant’Agnese, Anthony, Kolesar, Jill, Harris, Linda, Faerber, Adrienne, Havighurst, Thomas, Young, Jay M., Efros, Mitchell, Getzenberg, Robert H., Wheeler, Marcia A., Tangrea, Joseph, Parnes, Howard, House, Margaret, Busby, J. Erik, Hohl, Raymond, Bailey, Howard
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324663/
https://ncbi.nlm.nih.gov/pubmed/22293631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-11-0455
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