लोड हो रहा है...
Recognition of 1,N(2)-ethenoguanine by alkyladenine DNA glycosylase is restricted by a conserved active-site residue
The adenine, cytosine, and guanine bases of DNA are susceptible to alkylation by the aldehyde products of lipid peroxidation and by the metabolic byproducts of vinyl chloride pollutants. The resulting adducts spontaneously cyclize to form harmful etheno lesions. Cells employ a variety of DNA repair...
में बचाया:
| में प्रकाशित: | J Biol Chem |
|---|---|
| मुख्य लेखकों: | , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Society for Biochemistry and Molecular Biology
2020
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7008384/ https://ncbi.nlm.nih.gov/pubmed/31882538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011459 |
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