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Human Alkyladenine DNA Glycosylase Employs a Processive Search for DNA Damage

DNA repair proteins conduct a genome-wide search to detect and repair sites of DNA damage wherever they occur. Human alkyladenine DNA glycosylase (AAG) is responsible for recognizing a variety of base lesions, including alkylated and deaminated purines, and initiating their repair via the base excis...

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Detalhes bibliográficos
Main Authors: Hedglin, Mark, O’Brien, Patrick J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702167/
https://ncbi.nlm.nih.gov/pubmed/18839966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801046y
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