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Isolating Contributions from Intersegmental Transfer to DNA Searching by Alkyladenine DNA Glycosylase
Large genomes pose a challenge to DNA repair pathways because rare sites of damage must be efficiently located from among a vast excess of undamaged sites. Human alkyladenine DNA glycosylase (AAG) employs nonspecific DNA binding interactions and facilitated diffusion to conduct a highly redundant se...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3750153/ https://ncbi.nlm.nih.gov/pubmed/23839988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.477018 |
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