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Auto-kinase activity of Casein Kinase 1 δ/ε Governs the Period of Mammalian Circadian Rhythms

Circadian rhythms exist in nearly all organisms. In mammals, transcriptional and translational feedback loops (TTFLs) are believed to underlie the mechanism of the circadian clock. CK1δ/ε are key kinases that phosphorylate clock components such as PER proteins, determining the pace of the clock. Mos...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Rhythms
Hauptverfasser: Guo, Gaili, Wang, Kankan, Hu, Shan-Shan, Tian, Tian, Liu, Peng, Mori, Tetsuya, Chen, Peng, Johnson, Carl Hirschie, Qin, Ximing
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007343/
https://ncbi.nlm.nih.gov/pubmed/31392916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0748730419865406
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