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The Circadian Regulatory Proteins BMAL1 and Cryptochromes Are Substrates of Casein Kinase Iε

The serine/threonine protein kinase casein kinase I ε (CKIε) is a key regulator of metazoan circadian rhythm. Genetic and biochemical data suggest that CKIε binds to and phosphorylates the PERIOD proteins. However, the PERIOD proteins interact with a variety of circadian regulators, suggesting the p...

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Autori principali: Eide, Erik J., Vielhaber, Erica L., Hinz, William A., Virshup, David M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1513548/
https://ncbi.nlm.nih.gov/pubmed/11875063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111466200
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