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Auto-kinase activity of Casein Kinase 1 δ/ε Governs the Period of Mammalian Circadian Rhythms

Circadian rhythms exist in nearly all organisms. In mammals, transcriptional and translational feedback loops (TTFLs) are believed to underlie the mechanism of the circadian clock. CK1δ/ε are key kinases that phosphorylate clock components such as PER proteins, determining the pace of the clock. Mos...

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Détails bibliographiques
Publié dans:J Biol Rhythms
Auteurs principaux: Guo, Gaili, Wang, Kankan, Hu, Shan-Shan, Tian, Tian, Liu, Peng, Mori, Tetsuya, Chen, Peng, Johnson, Carl Hirschie, Qin, Ximing
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007343/
https://ncbi.nlm.nih.gov/pubmed/31392916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0748730419865406
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