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Auto-kinase activity of Casein Kinase 1 δ/ε Governs the Period of Mammalian Circadian Rhythms

Circadian rhythms exist in nearly all organisms. In mammals, transcriptional and translational feedback loops (TTFLs) are believed to underlie the mechanism of the circadian clock. CK1δ/ε are key kinases that phosphorylate clock components such as PER proteins, determining the pace of the clock. Mos...

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Detalhes bibliográficos
Publicado no:J Biol Rhythms
Main Authors: Guo, Gaili, Wang, Kankan, Hu, Shan-Shan, Tian, Tian, Liu, Peng, Mori, Tetsuya, Chen, Peng, Johnson, Carl Hirschie, Qin, Ximing
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007343/
https://ncbi.nlm.nih.gov/pubmed/31392916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0748730419865406
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