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Auto-kinase activity of Casein Kinase 1 δ/ε Governs the Period of Mammalian Circadian Rhythms

Circadian rhythms exist in nearly all organisms. In mammals, transcriptional and translational feedback loops (TTFLs) are believed to underlie the mechanism of the circadian clock. CK1δ/ε are key kinases that phosphorylate clock components such as PER proteins, determining the pace of the clock. Mos...

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Publicado en:J Biol Rhythms
Autores principales: Guo, Gaili, Wang, Kankan, Hu, Shan-Shan, Tian, Tian, Liu, Peng, Mori, Tetsuya, Chen, Peng, Johnson, Carl Hirschie, Qin, Ximing
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007343/
https://ncbi.nlm.nih.gov/pubmed/31392916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0748730419865406
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