Molecular Signatures of Neuroinflammation Induced by αSynuclein Aggregates in Microglial Cells

Alpha-synuclein (αSyn(Agg)) are pathological hallmarks of Parkinson's disease (PD) and other synucleinopathies that induce microglial activation and immune-mediated neurotoxicity, but the molecular mechanisms of αSyn(Agg)-induced immune activation are poorly defined. We performed quantitative p...

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Publicat a:Front Immunol
Autors principals: Sarkar, Souvarish, Dammer, Eric B., Malovic, Emir, Olsen, Abby L., Raza, Syed Ali, Gao, Tianwen, Xiao, Hailian, Oliver, Danielle L., Duong, Duc, Joers, Valerie, Seyfried, Nicholas, Huang, Meixiang, Kukar, Thomas, Tansey, Malú G., Kanthasamy, Anumantha G., Rangaraju, Srikant
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7006296/
https://ncbi.nlm.nih.gov/pubmed/32082315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00033
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