Molecular Signatures of Neuroinflammation Induced by αSynuclein Aggregates in Microglial Cells

Alpha-synuclein (αSyn(Agg)) are pathological hallmarks of Parkinson's disease (PD) and other synucleinopathies that induce microglial activation and immune-mediated neurotoxicity, but the molecular mechanisms of αSyn(Agg)-induced immune activation are poorly defined. We performed quantitative p...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Sarkar, Souvarish, Dammer, Eric B., Malovic, Emir, Olsen, Abby L., Raza, Syed Ali, Gao, Tianwen, Xiao, Hailian, Oliver, Danielle L., Duong, Duc, Joers, Valerie, Seyfried, Nicholas, Huang, Meixiang, Kukar, Thomas, Tansey, Malú G., Kanthasamy, Anumantha G., Rangaraju, Srikant
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7006296/
https://ncbi.nlm.nih.gov/pubmed/32082315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00033
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