Transcriptional regulation of homeostatic and disease-associated-microglial genes by IRF1, LXRβ and CEBPα

Microglia transform from homeostatic to disease-associated-microglia (DAM) profiles in neurodegeneration. Within DAM, we recently identified distinct pro-inflammatory and anti-inflammatory sub-profiles although the transcriptional regulators of homeostatic and distinct DAM gene profiles in microglia...

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發表在:Glia
Main Authors: Gao, Tianwen, Jernigan, Janna, Raza, Syed Ali, Dammer, Eric B, Xiao, Hailian, Seyfried, Nicholas T, Levey, Allan I, Rangaraju, Srikant
格式: Artigo
語言:Inglês
出版: 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190149/
https://ncbi.nlm.nih.gov/pubmed/31301160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23678
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