Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer’s disease

BACKGROUND: Disease-associated-microglia (DAM) represent transcriptionally-distinct and neurodegeneration-specific microglial profiles with unclear significance in Alzheimer’s disease (AD). An understanding of heterogeneity within DAM and their key regulators may guide pre-clinical experimentation a...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Mol Neurodegener
Huvudupphovsmän: Rangaraju, Srikant, Dammer, Eric B., Raza, Syed Ali, Rathakrishnan, Priyadharshini, Xiao, Hailian, Gao, Tianwen, Duong, Duc M., Pennington, Michael W., Lah, James J., Seyfried, Nicholas T., Levey, Allan I.
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2018
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963076/
https://ncbi.nlm.nih.gov/pubmed/29784049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-018-0254-8
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk