Manganese Activates NLRP3 Inflammasome Signaling and Propagates Exosomal Release of ASC in Microglial Cells

Chronic sustained inflammation underlies many pathological conditions including neurodegenerative diseases. Divalent manganese (Mn) exposure can stimulate neurotoxicity by increasing inflammation. In this study, we examined whether Mn activates the NLRP3 inflammasome to prime neuroinflammation. Expo...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Sarkar, Souvarish, Rokad, Dharmin, Malovic, Emir, Luo, Jie, Harischandra, Dilshan S, Jin, Huajun, Anantharam, Vellareddy, Huang, Xuemei, Lewis, Mechelle, Kanthasamy, Arthi, Kanthasamy, Anumantha G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420319/
https://ncbi.nlm.nih.gov/pubmed/30622196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aat9900
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados