Environmental Neurotoxicant Manganese Regulates Exosome-mediated Extracellular miRNAs in Cell Culture Model of Parkinson’s Disease: Relevance to α-Synuclein Misfolding in Metal Neurotoxicity

Many chronic neurodegenerative disorders share a common pathogenic mechanism involving the aggregation and deposition of misfolded proteins. Recently, it was shown that these aggregated proteins could be transferred from one cell to another via extracellular nanovesicles called exosomes. Initially t...

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Publicado no:Neurotoxicology
Main Authors: Harischandra, Dilshan S., Ghaisas, Shivani, Rokad, Dharmin, Zamanian, Mostafa, Jin, Huajun, Anantharam, Vellareddy, Kimber, Michael, Kanthasamy, Arthi, Kanthasamy, Anumantha
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654692/
https://ncbi.nlm.nih.gov/pubmed/28450057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2017.04.007
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