Environmental Neurotoxicant Manganese Regulates Exosome-mediated Extracellular miRNAs in Cell Culture Model of Parkinson’s Disease: Relevance to α-Synuclein Misfolding in Metal Neurotoxicity

Many chronic neurodegenerative disorders share a common pathogenic mechanism involving the aggregation and deposition of misfolded proteins. Recently, it was shown that these aggregated proteins could be transferred from one cell to another via extracellular nanovesicles called exosomes. Initially t...

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Опубликовано в: :Neurotoxicology
Главные авторы: Harischandra, Dilshan S., Ghaisas, Shivani, Rokad, Dharmin, Zamanian, Mostafa, Jin, Huajun, Anantharam, Vellareddy, Kimber, Michael, Kanthasamy, Arthi, Kanthasamy, Anumantha
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654692/
https://ncbi.nlm.nih.gov/pubmed/28450057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2017.04.007
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