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Manganese exposure induces neuroinflammation by impairing mitochondrial dynamics in astrocytes

Chronic manganese (Mn) exposure induces neurotoxicity, which is characterized by Parkinsonian symptoms resulting from impairment in the extrapyramidal motor system of the basal ganglia. Mitochondrial dysfunction and oxidative stress are considered key pathophysiological features of Mn neurotoxicity....

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Vydáno v:Neurotoxicology
Hlavní autoři: Sarkar, Souvarish, Malovic, Emir, Harischandra, Dilshan S., Ngwa, Hilary A., Ghosh, Anamitra, Hogan, Colleen, Rokad, Dharmin, Zenitsky, Gary, Jin, Huajun, Anantharam, Vellareddy, Kanthasamy, Anumantha G., Kanthasamy, Arthi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698176/
https://ncbi.nlm.nih.gov/pubmed/28539244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2017.05.009
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