ATF6 Is a Critical Determinant of CHOP Dynamics during the Unfolded Protein Response

The unfolded protein response (UPR) pathway senses unfolded proteins and regulates proteostasis and cell fate through activity of the transcription factors ATF4, ATF6, and XBP1 within a complex network of three main branches. Here, we investigated contributions of the three branches to UPR activity...

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Détails bibliographiques
Publié dans:iScience
Auteurs principaux: Yang, Huan, Niemeijer, Marije, van de Water, Bob, Beltman, Joost B.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7005498/
https://ncbi.nlm.nih.gov/pubmed/32058971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.100860
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