ATF6 Is a Critical Determinant of CHOP Dynamics during the Unfolded Protein Response

The unfolded protein response (UPR) pathway senses unfolded proteins and regulates proteostasis and cell fate through activity of the transcription factors ATF4, ATF6, and XBP1 within a complex network of three main branches. Here, we investigated contributions of the three branches to UPR activity...

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Bibliographic Details
Published in:iScience
Main Authors: Yang, Huan, Niemeijer, Marije, van de Water, Bob, Beltman, Joost B.
Format: Artigo
Language:Inglês
Published: Elsevier 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7005498/
https://ncbi.nlm.nih.gov/pubmed/32058971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.100860
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