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ATF6 Is a Critical Determinant of CHOP Dynamics during the Unfolded Protein Response

The unfolded protein response (UPR) pathway senses unfolded proteins and regulates proteostasis and cell fate through activity of the transcription factors ATF4, ATF6, and XBP1 within a complex network of three main branches. Here, we investigated contributions of the three branches to UPR activity...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Yang, Huan, Niemeijer, Marije, van de Water, Bob, Beltman, Joost B.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7005498/
https://ncbi.nlm.nih.gov/pubmed/32058971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.100860
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