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ATF6 Is a Critical Determinant of CHOP Dynamics during the Unfolded Protein Response

The unfolded protein response (UPR) pathway senses unfolded proteins and regulates proteostasis and cell fate through activity of the transcription factors ATF4, ATF6, and XBP1 within a complex network of three main branches. Here, we investigated contributions of the three branches to UPR activity...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:iScience
Prif Awduron: Yang, Huan, Niemeijer, Marije, van de Water, Bob, Beltman, Joost B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7005498/
https://ncbi.nlm.nih.gov/pubmed/32058971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.100860
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