The RUNX1-ETO target gene RASSF2 suppresses t(8;21) AML development and regulates Rac GTPase signaling

Large-scale chromosomal translocations are frequent oncogenic drivers in acute myeloid leukemia (AML). These translocations often occur in critical transcriptional/epigenetic regulators and contribute to malignant cell growth through alteration of normal gene expression. Despite this knowledge, the...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Blood Cancer J
Main Authors: Stoner, Samuel A., Liu, Katherine Tin Heng, Andrews, Elizabeth T., Liu, Mengdan, Arimoto, Kei-Ichiro, Yan, Ming, Davis, Amanda G., Weng, Stephanie, Dow, Michelle, Xian, Su, DeKelver, Russell C., Carter, Hannah, Zhang, Dong-Er
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7005177/
https://ncbi.nlm.nih.gov/pubmed/32029705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41408-020-0282-9
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados