Computational saturation mutagenesis to predict structural consequences of systematic mutations in the beta subunit of RNA polymerase in Mycobacterium leprae

Rifampin resistance in leprosy may remain undetected due to the lack of rapid and effective diagnostic tools. A quick and reliable method is essential to determine the impacts of emerging detrimental mutations in the drug targets. The functional consequences of missense mutations in the β-subunit of...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Comput Struct Biotechnol J
Huvudupphovsmän: Vedithi, Sundeep Chaitanya, Rodrigues, Carlos H.M., Portelli, Stephanie, Skwark, Marcin J., Das, Madhusmita, Ascher, David B., Blundell, Tom L., Malhotra, Sony
Materialtyp: Artigo
Språk:Inglês
Publicerad: Research Network of Computational and Structural Biotechnology 2020
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000446/
https://ncbi.nlm.nih.gov/pubmed/32042379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.01.002
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk