Structure-Guided Computational Approaches to Unravel Druggable Proteomic Landscape of Mycobacterium leprae

Leprosy, caused by Mycobacterium leprae (M. leprae), is treated with a multidrug regimen comprising Dapsone, Rifampicin, and Clofazimine. These drugs exhibit bacteriostatic, bactericidal and anti-inflammatory properties, respectively, and control the dissemination of infection in the host. However,...

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Bibliografische gegevens
Gepubliceerd in:Front Mol Biosci
Hoofdauteurs: Vedithi, Sundeep Chaitanya, Malhotra, Sony, Acebrón-García-de-Eulate, Marta, Matusevicius, Modestas, Torres, Pedro Henrique Monteiro, Blundell, Tom L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2021
Onderwerpen:
Molecular Biosciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8138464/
https://ncbi.nlm.nih.gov/pubmed/34026836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.663301
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