Patient-derived glioblastoma cultures as a tool for small-molecule drug discovery

There is a compelling need for new therapeutic strategies for glioblastoma multiforme (GBM). Preclinical target and therapeutic discovery for GBMs is primarily conducted using cell lines grown in serum-containing media, such as U-87 MG, which do not reflect the gene expression profiles of tumors fou...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ye, Ling F., Reznik, Eduard, Korn, Joshua M., Lin, Fallon, Yang, Guizhi, Malesky, Kimberly, Gao, Hui, Loo, Alice, Pagliarini, Raymond, Mikkelsen, Tom, Lo, Donald C., deCarvalho, Ana C., Stockwell, Brent R.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996910/
https://ncbi.nlm.nih.gov/pubmed/32064048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27457
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