Patient-derived glioblastoma cultures as a tool for small-molecule drug discovery

There is a compelling need for new therapeutic strategies for glioblastoma multiforme (GBM). Preclinical target and therapeutic discovery for GBMs is primarily conducted using cell lines grown in serum-containing media, such as U-87 MG, which do not reflect the gene expression profiles of tumors fou...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Ye, Ling F., Reznik, Eduard, Korn, Joshua M., Lin, Fallon, Yang, Guizhi, Malesky, Kimberly, Gao, Hui, Loo, Alice, Pagliarini, Raymond, Mikkelsen, Tom, Lo, Donald C., deCarvalho, Ana C., Stockwell, Brent R.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2020
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996910/
https://ncbi.nlm.nih.gov/pubmed/32064048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27457
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