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Dissect the DNMT3A- and DNMT3B-mediated DNA co-methylation through a covalent complex approach

DNA methylation plays a critical role in regulating gene expression, genomic stability and cell fate commitment. Mammalian DNA methylation, which mostly occurs in the context of CpG dinucleotide, is installed by two do novo DNA methyltransferases, DNMT3A and DNMT3B. Oligomerization of DNMT3A and DNM...

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Detaylı Bibliyografya
Yayımlandı:J Mol Biol
Asıl Yazarlar: Gao, Linfeng, Anteneh, Hiwot, Song, Jikui
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6995754/
https://ncbi.nlm.nih.gov/pubmed/31726062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.11.004
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