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Dissect the DNMT3A- and DNMT3B-mediated DNA co-methylation through a covalent complex approach

DNA methylation plays a critical role in regulating gene expression, genomic stability and cell fate commitment. Mammalian DNA methylation, which mostly occurs in the context of CpG dinucleotide, is installed by two do novo DNA methyltransferases, DNMT3A and DNMT3B. Oligomerization of DNMT3A and DNM...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Mol Biol
Egile Nagusiak: Gao, Linfeng, Anteneh, Hiwot, Song, Jikui
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6995754/
https://ncbi.nlm.nih.gov/pubmed/31726062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.11.004
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