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An Update on the Structure of hERG
The human voltage-sensitive K(+) channel hERG plays a fundamental role in cardiac action potential repolarization, effectively controlling the QT interval of the electrocardiogram. Inherited loss- or gain-of-function mutations in hERG can result in dangerous “long” (LQTS) or “short” QT syndromes (SQ...
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| Gepubliceerd in: | Front Pharmacol |
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| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Frontiers Media S.A.
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6992539/ https://ncbi.nlm.nih.gov/pubmed/32038248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01572 |
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