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An Update on the Structure of hERG

The human voltage-sensitive K(+) channel hERG plays a fundamental role in cardiac action potential repolarization, effectively controlling the QT interval of the electrocardiogram. Inherited loss- or gain-of-function mutations in hERG can result in dangerous “long” (LQTS) or “short” QT syndromes (SQ...

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Bibliografiska uppgifter
I publikationen:Front Pharmacol
Huvudupphovsmän: Butler, Andrew, Helliwell, Matthew V., Zhang, Yihong, Hancox, Jules C., Dempsey, Christopher E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6992539/
https://ncbi.nlm.nih.gov/pubmed/32038248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01572
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