Action potential clamp characterization of the S631A hERG mutation associated with short QT syndrome

The hERG potassium channel is critical to normal repolarization of cardiac action potentials (APs) and loss‐ and gain‐of‐function hERG mutations are associated, respectively, with long and short QT syndromes, pathological conditions that can lead to arrhythmias and sudden death. hERG current (I (h)...

Full description

Saved in:
Bibliographic Details
Published in:Physiol Rep
Main Authors: Butler, Andrew, Zhang, Yihong, Stuart, Alan G., Dempsey, Christopher E., Hancox, Jules C.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6119704/
https://ncbi.nlm.nih.gov/pubmed/30175559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13845
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items