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Action potential clamp characterization of the S631A hERG mutation associated with short QT syndrome

The hERG potassium channel is critical to normal repolarization of cardiac action potentials (APs) and loss‐ and gain‐of‐function hERG mutations are associated, respectively, with long and short QT syndromes, pathological conditions that can lead to arrhythmias and sudden death. hERG current (I (h)...

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Podrobná bibliografie
Vydáno v:Physiol Rep
Hlavní autoři: Butler, Andrew, Zhang, Yihong, Stuart, Alan G., Dempsey, Christopher E., Hancox, Jules C.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6119704/
https://ncbi.nlm.nih.gov/pubmed/30175559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13845
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