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Nuclear and Cytoplasmatic Quantification of Unconjugated, Label-Free Locked Nucleic Acid Oligonucleotides

Methods for the quantification of antisense oligonucleotides (AONs) provide insightful information on biodistribution and intracellular trafficking. However, the established methods have not provided information on the absolute number of molecules in subcellular compartments or about how many AONs a...

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Dades bibliogràfiques
Publicat a:Nucleic Acid Ther
Autors principals: Pendergraff, Hannah, Schmidt, Steffen, Vikeså, Jonas, Weile, Christian, Øverup, Charlotte, W. Lindholm, Marie, Koch, Troels
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc., publishers 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6987631/
https://ncbi.nlm.nih.gov/pubmed/31618108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2019.0810
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