Efficient gene silencing by delivery of locked nucleic acid antisense oligonucleotides, unassisted by transfection reagents

For the past 15–20 years, the intracellular delivery and silencing activity of oligodeoxynucleotides have been essentially completely dependent on the use of a delivery technology (e.g. lipofection). We have developed a method (called ‘gymnosis’) that does not require the use of any transfection rea...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Stein, C. A., Hansen, J. Bo, Lai, Johnathan, Wu, SiJian, Voskresenskiy, Anatoliy, Høg, Anja, Worm, Jesper, Hedtjärn, Maj, Souleimanian, Naira, Miller, Paul, Soifer, Harris S., Castanotto, Daniella, Benimetskaya, Luba, Ørum, Henrik, Koch, Troels
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2010
Gaiak:
Methods Online
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800216/
https://ncbi.nlm.nih.gov/pubmed/19854938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp841
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